The Use of Medical Devices for Medical Skin Care and the Legal Issues / 대한피부과학회지

BACKGROUND: Medical skin care is essential for the treatment of skin diseases all over the world. Medical skin care is also part of medical practice and this must be differentiated from the simple skin care that is given for normal healthy skin. OBJECTIVE: We wanted to discuss medical skin care and the related medical devices and legal issues. METHODS: We reviewed the related laws and regulations, we consulted experts and associations and we analyzed the result of the survey. RESULTS: Legally, medical skin care and simple skin care are well classified. However, many illegal procedures are still performed by non-medical personnel and many adverse effects have been reported as a result. Furthermore, there are no legal restrictions for the performer based on the grade of each medical skin care procedure. CONCLUSION: For the best results and safe procedures, medical skin care must be performed by approved medical equipment under the supervision of a physician or medical personnel. Continuous control and guidance by the government is strongly needed.

Separation of Human Epidermal Cells by Using Percoll / 대한피부과학회지

The epidermis, which is composed mainly of keratinocyt;es, undergoes continual proliferation and differentiation, To study keratinocyte differentiation, it is necessary to separate the keratinocytes at their sucessive stages of maturation. We separate the keratinocytes by layers by using Percoll and obtain the relatively pure fractions of basal cells, spinous cells, and granular cells, 76. 8%, 67. 2%, 30%. respectively.

A Case of Epidermodysplasia Verruciformis Associated with Bowen's Disease / 대한피부과학회지

We present a case of epidermodysplasia verruciformis a.ssociated with Bowen's disease. Patient was 33 year-old male and his skin lesions showed diffuse flat papules on face and neck, many brownish papules on trunk and papillomatous tumors also appeared un scalp and post auricular area, Skin biopsy findings from the flat papular lesion showed histopathologic features of verruca plana and from the papillomatous lesion showed the feature of Bowen's disease. Electron microscopic finding from the flat papular lesion showed marked aggregates of viral particles around the nuclei of epidermal keratinocytes.

Effect of Acupuncture on Histamine Induced Itch / 대한피부과학회지

We cairried out this study to find the possibility of itch control with acupuncture under the hypothesis that antipruritic effect also exists if the itch sensation is closely allied to pain. We evaluated the effect of acupuncture on histarnine induced itch, flare and wheal in 20 healthy male volunteers aged 24 32 years old and compared it with the effect of pseudoacupuncture on them and that of no intervention on them. The results were as follows: 1. Mans of itch intensity and duration were decreased in A(session with acupuncture) and P(session with Pseudoacupuncture), compared to those of N(session with no intervention), and A was more effective in decreasing the itch intensity and its duration than P. 2. Means of maximal sizes of flare and wheal were smaller in A and P, but there was no remarkable difference between A and P.

Phytophotodermatitis / 대한피부과학회지

We describe herein a 3 family members with phytophotodermatitis. After fig (juice) was applied to skin for the purpose of treating psoriasis in a 30 year-old woman and applied incidentally in her mother and 3 year-old daughter, vesicobullous eruptions developed immediately after sun-exposure, predominantly in the sun-exposed area. ln histopathology, the epidermis shows intraepidermal separation with necrosis and reepithelization on basal layer and marked spongiosis. We treated with systemic steroid, wet dressing with burow solution etc, so she healed without sequela after 2 weeks.

Quantitative Analysis of Interferon Levels in Serum of Patinets with Varicella-Zoster Virus Infection / 대한피부과학회지

Recently, the importance of interferons as immune modulators has been recognized. Measurement of serum or tissue levels give only a partial picture of interferon activity, since antiviral effects persist after levels become undetectable. Neverthless, serum levels correlate reasonably well with clinical effects. Authors have analyzed the serum interferon levels in 12 patients with varicelIa and 25 with herpes zoster and the results are compared with healthy normal control. The results are as follows. The mean value of serum interferon levels showed no significant difference between patients group with varicella and with herpes zoster (8. 4+8, 5units/ml) and normal healthy control group (6. 2+7. 2 units/ml), 2, The mean value of serum interferon levels showed no significant difference between patients group with varicella (9. 2+7. 8 unit/ml) and normal healthy control group. 3 The mean value of serum interferon levels showed no significant difference between patients group with herpes zoster (8. I+9. 0 units/ml) and normal healthy control group. 4 The mean value of serum interferon levels showed no significant difference between patients group of varicella and those of herpes zoster.

A Case of Epidermolysis Bullosa Dystrophica / 대한피부과학회지

Epidermolysis bullosa dystrophica(EBD) is a rare, hereditary and chronic mechanobullous disease characterized by blistering and erosions of the skin in response to even minor trauma. A 5-year old girl visited with a complaint of continuous vesicobullous skin eruptions since birth. On examination, bullae, vesicles, atrophic scars, crusts and ero:ions were scattered on whole body. Loss of finger and toe nails, partial syndactyly of all toe webs and milia on dorsa of feet were noticed. We present a case of EBD that seems to be a recessive type considering the absence of family history with histopathologic and electron microscopic findings.

A Case of Fox-Fordyce Disease / 대한피부과학회지

Fox-Fordyce disease is a chronic pruritic papular eiruption, usually appearing in women and presenting a strict localization to the areas bearing apocrine sweat glands. More than 90g, of the cases were seen in women, the majority being in the age group of 13 to 35 years. The present report deals with unusual case of 14-year-old boy who developed Fox-Fordyce disease 6 years ago. To our knowledge, it is extremely rare case in Korea.

A Case of Subcutaneous Fat Necrosis of Newborn / 대한피부과학회지

Authors experienced a 13-day-old boy who had suffered from walnut sized hard erythematous nodules on left axilla, anterior and posterior aspect of the neck which began to develop 9 days after birth. Histopathologic findings revealed subcutaneous fat necrosis and needle-shaped cleft in several fat cells. The skin lesions spontaneously resolved at 2 months of age. The clinical pattern, the skin manifestations, and the histologic appearance of the lesions were diagnostic of subcutaneous fat necrosis of newborn.

A Case of Lymphomatoid Granulomatosis / 대한피부과학회지

We report a case of Lymphomatoid granulomatosis in a 54-year-old woman. She presented with a two months history of a tender nodule located on the left for earm associated with fever and pulmonary symptoma aggravated against various treatments. She died 92 days of admission because of respiratory failure. Diagnosis was based on the clinical features and histopathologic findings of the skin lesion.

A Case of Juvenile Xanthogranuloma Associated with Cranial Bone Lesion / 대한피부과학회지

Juvenile xanthogranuloma is a benign disseminated xanthomatous and granulomatous condition of the skin and other organs. The skin lesions usually disappear spontaneously within 1 to 5 years. Our case was 4 month-old boy who had have match head to pea sized scattered yellowish papules and nodules on scrotum since age of 1 month and then these skin lesions gradually spread to trunk, face and scalp without subjective symptoms. Histopathologically, biopsy specimen of the trunk revealed massive accumulation of histiocytes at dermis. With fat stain, fat substance is demonstrated within the foamy histiocytes. The skull x-ray revealed coin sized, well circumscribed osteolytic lesion on the left parietal bone. By the age of two and half, most of the skin lesions and bone defect on skull x-ray disappeared spontaneously.

Immune Cells (T Cell, T Subsets and B Cell) in the Peripheral Blood of Patients with Psoriasis and Effects of Photochemotherapy (PUVA) on These Cells / 대한피부과학회지

Recent studies have demonstrated that the patients with psoriasis have various immune alternation in both humoral and cellular immunities. However the results of these are still controversial. These facts promoted us to analyze the immune cells (T cell, T subsets and B cell) by rosette method for these cells in peripheral blood of 15 patients with psoriasis. And we also analyzed the effects of photo- chemotherapy(PUVA) on these cells. The results were summerized as follows; 1. The mean values of T cell, T, T, cell and B cell in peripheral blood of the- patients with psoriasis before PUVA therapy were 56. 2+-5.7%, 35.1+-6.9%, 5. 5+l.4%, 11.6+4. 0% respectively, These results of immune cells showed signi- ficantly lower mean values when these were compaired with the mean values. of nomnal control group(T cell; 65. 2+-2.9%, TM cell; 45.8+-3.2%, T cell; 7.3+ 1.3% B cell; 16.2+2.4%), respectively (T cell, Tm Tg, p<0.01, B cell; p<0.05). 2. The mean values of T cell, T, T, cell and B cell in peripheral blood (countinue..)

Erythema Dyschromicum Perstans: Report of Three Cases / 대한피부과학회지

We observed three patients who showed widespread macular ashy-colored eruptions. They fit clinically and histopathologically with the typical erythema dyschromicum perstans (ashy dermatosis). Erythoma dyschromicum perstans is a peculiar pigmented condition of unknown etiology characterized by persistent ashy-gray colored macule, refractory to any modality. All of them have similar skin lesions which are multiple, variable sized oval-shaped, ash-colored macular eruption on the trunk and extremities. Histologic findings of 2 patients reveal the characteristic feature of focal hydropic degeneration of the basal cell layer of the epidermis, perivascular infiltrates of lymphocytes and histiocytes and melanin-laden macrophages in the corium, however, merely pigmentary incontinence into the corium in 1 patient. Literatures are briefly reviewed.